| Titel |
Molekulare Pathogenese Aggressiver Lymphome  
|
| Title |
Molecular Pathogenesis of Aggressive Lymphoma |
| Schwerpunkt/Focus |
|
| Sprache/Language |
englisch
deutsch |
| VV-Nr./Course No. |
136316 |
| Modulverantwortlich/Responsible |
Dr. C. Kosnopfel |
| Vertreter/Co-responsible |
Prof. Dr. G. Lenz |
| Anbieter/Teachers |
Dr. C. Kosnopfel, Prof. Dr. G. Lenz |
| Typ/Type |
Praktikum |
| SWS/Semerster periods per week |
|
| Arbeitslast(h)/Work load |
300 h |
| KP/Credit points |
10 KP |
| Zuordnung/Classification |
Forschungs-Modul |
| Semester/Semester |
SoSe
WiSe |
| Studierende/Students |
MSc Biowissenschaften
MSc Biotechnologie
MSc Molekulare Biomedizin |
| Corona-Informationen/Corona-Information |
|
| Zeit/Date |
by agreement (8 weeks) |
| Ort/Location |
Forschungslabor Med. Klinik A, Domagkstr. 3, 3. OG |
| Beginn/Start |
by agreement |
| Vorbesprechung/Obligatory pre-meeting |
by agreement |
| Voraussetzung/Prerequisite |
none |
| Anmeldung/Registration |
corinnaveronica.kosnopfel@ukmuenster.de |
| Leistungskontrollen/Performance assessments |
oral presentation, written protocol |
| Termine f. Leistungskontrollen/Date for performance assessments |
by agreement |
| max. NP/Max. grade points |
200 |
| Ziele/Aims |
Students will learn the molecular pathomechanisms underlying the development and progression of lymphoma and how to study them experimentally. |
| Inhalte/Content |
- mechanisms of lymphoma development, progression and therapy resistance
- classification of lymphomas based on molecular alterations
- identification of therapeutic options and potential biomarkers for distinct lymphoma subgroups
- basic state-of-the-art laboratory techniques
- development of experimental setups
- data analysis
|
| Methoden/Methods |
- cell culture (cell lines, co-culture models)
- genetic modification of cells (transfection, transduction; gene overexpression, knockdown, knockout via CRISPR/Cas9)
- functional assays (proliferation, apoptosis, invasion, migration)
- protein biochemical methods (Western Blot, ELISA, FACS)
- molecular biological methods (cloning, RNA isolation, cDNA synthesis, qPCR)
|
| Berufsrelevante und interdisziplinäre Komponenten/Occupational and interdisciplinary skills |
|
| Voraussetzung für/Prerequisite for |
|
| Präsenzpflicht/Compulsory presence |
yes |
| Plätze/Number of participants |
1-2 |
| Gruppengröße/Group size |
1 |
| Materialien/Materials |
none |
| Literatur/Literature |
Literature will be provided and discussed individually prior to the start of the research project |
| Links |
|
| Sonstiges/Further information |
|
= Modul gehört zum SPP Imoplant / Module is part of the SSP Imoplant
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= Modul gehört zum SPP Neuroscience and Behaviour /Module is part of the SSP Neuroscience and Behaviour
= Modul gehört zum SPP Quantitative Cell Biology /Module is part of the SSP Quantitative Cell Biology