Veranstaltung
| Titel | Von der Pathogenese zur Präzisionsmedizin bei aggressiven Lymphomen |
| Title | From Pathogenesis to Precision Medicine in Aggressive Lymphomas |
| Schwerpunkt/Focus | |
| Sprache/Language | optional |
| VV-Nr./Course No. | |
| Modulverantwortlich/Responsible | Dr. C. Kosnopfel |
| Vertreter/Co-responsible | Prof. Dr. G. Lenz |
| Anbieter/Teachers | Dr. C. Kosnopfel; Prof. Dr. G. Lenz |
| Typ/Type | Praktikum |
| SWS/Semerster periods per week | |
| Arbeitslast(h)/Work load | 5 KP |
| KP/Credit points | 5 KP |
| Zuordnung/Classification | Fortgeschrittenen-Modul |
| Semester/Semester | SoSe WiSe |
| Studierende/Students | MSc Biowissenschaften MSc Biotechnologie MSc Molekulare Biomedizin |
| Corona-Informationen/Corona-Information | |
| Zeit/Date | by agreement (4 weeks) |
| Ort/Location | Forschungslabor Med. Klinik A |
| Beginn/Start | by agreement |
| Vorbesprechung/Obligatory pre-meeting | by agreement |
| Voraussetzung/Prerequisite | none |
| Anmeldung/Registration | Online Anmeldung |
| Leistungskontrollen/Performance assessments | oral presentation, written protocol |
| Termine f. Leistungskontrollen/Date for performance assessments | by agreement |
| max. NP/Max. grade points | 200 |
| Ziele/Aims | Students will learn the molecular pathomechanisms underlying the development and progression of lymphoma and how to exploit them for therapeutic purposes. |
| Inhalte/Content | - mechanisms of lymphoma development, progression and therapy resistance - classification of lymphomas based on molecular alterations - identification of therapeutic options and potential biomarkers for distinct lymphoma subgroups - basic state-of-the-art laboratory techniques - development of experimental setups - data analysis |
| Methoden/Methods | - cell culture (cell lines, co-culture models) - genetic modification of cells (transfection, transduction; gene overexpression, knockdown, knockout via CRISPR/Cas9) - functional assays (proliferation, apoptosis, invasion, migration) - protein biochemical methods (Western Blot, ELISA, FACS) - molecular biological methods (cloning, RNA isolation, cDNA synthesis, qPCR) |
| Berufsrelevante und interdisziplinäre Komponenten/Occupational and interdisciplinary skills | |
| Voraussetzung für/Prerequisite for | |
| Präsenzpflicht/Compulsory presence | yes |
| Plätze/Number of participants | 1 |
| Gruppengröße/Group size | 1 |
| Materialien/Materials | none |
| Literatur/Literature | Literature will be provided and discussed individually prior to the start of the research project |
| Links | https://web.ukm.de/meda-forschung-lehre/ag-lenz-aggressive-lymphome |
| Sonstiges/Further information |
Modulelemente:
Elemente of the module:
| Titel/Title | Zeit (von...bis)/Time (from...to) | Ort(Raum)/Location | |
|---|---|---|---|
| Übungen/Practical exercises | |||
| Vorlesung/Lecture | |||
| Seminare/Semeinars | |||
| Exkursionen/Excursions |
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